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Thursday 30 August 2018

Cell Metabolism for Combating Cancer Tumor


New treatment methods, new discoveries and researches are emerging in this period, when four cardiac specialists work to fight cancer. One of these is the use of cell metabolism to remove the cancerous tumor from the center. Of course, we need to know what cell metabolism means first of all to understand this. We present all the details to you, and if you have any problems, you can contact us in the comments section.

A better understanding of metabolism in tumor cells that evade drugs could improve cancer treatments, according to new research from the University of Cincinnati in Ohio.

Some tumors are hard to treat because while at first they respond to cancer drugs, some cells are able to survive and seed new tumors.

The surviving cells do this by increasing a "self-eating" process through which they eliminate waste, remove faulty components and pathogens, and recycle essential molecular building blocks.

The process, known as autophagy, delivers the waste to cell compartments called lysosomes. These contain different types of enzymes for digesting and breaking down the various materials.

Autophagy is also a survival mechanism that switches on when nutrients are scarce and switches off again when nutrients are plentiful.

"We found that cell metabolism significantly influences the ability to begin autophagy," says lead investigator Carol Mercer, an associate professor in the Division of Hematology and Oncology at the University of Cincinnati in Ohio.


She and her colleagues report their findings — which reveal "the dynamic and metabolic regulation of autophagy" — in a paper that is now published in the journal Cell Reports.

Source: https://www.medicalnewstoday.com/articles/322927.php

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